Benzophenone

Benzophenone

SCHEMBL28746428

Nc1ccccc1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.75
ALDH1A1 P00352 2/20 0.74
TDP1 Q9NUW8 2/20 0.61
L3MBTL1 Q9Y468 2/20 0.61
ATM Q13315 1/20 0.61
SRD5A2 P31213 1/20 0.61
TSHR P16473 3/20 0.58
MAPT P10636 3/20 0.58
GAA P10253 1/20 0.58
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
HSD17B10 Q99714 2/20 0.52
POLB P06746 1/20 0.52
CYP3A4 P08684 1/20 0.52
PARP1 P09874 1/20 0.52
CYP2C19 P33261 1/20 0.52
RECQL P46063 1/20 0.52
BLM P54132 1/20 0.52
PMP22 Q01453 1/20 0.52
LMNA P02545 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL28805655 0.97 PBRM1 (0.72) PBRM1ALDH1A1TDP1L3MBTL1ATM
SCHEMBL49952 0.92 ALDH1A1 (0.70) PBRM1ALDH1A1TDP1L3MBTL1ATM
Bicarbonate SCHEMBL27627699 0.90 ALDH1A1 (0.67) PBRM1ALDH1A1TDP1L3MBTL1ATM
Hydrochloric Acid SCHEMBL8746067 0.90 ALDH1A1 (0.67) PBRM1ALDH1A1TDP1L3MBTL1ATM
Ammonia Solution, Strong SCHEMBL28612928 0.90 ALDH1A1 (0.67) PBRM1ALDH1A1TDP1L3MBTL1ATM
Nitrogen SCHEMBL261314 0.88 ALDH1A1 (0.64) PBRM1ALDH1A1TDP1L3MBTL1ATM
Ammonia Solution, Strong SCHEMBL28281325 0.88 ALDH1A1 (0.64) PBRM1ALDH1A1TDP1L3MBTL1ATM
SCHEMBL9492773 0.86 MEN1 (0.67) PBRM1ALDH1A1TDP1L3MBTL1ATM
SCHEMBL147608 0.86 PBRM1 (1.00) PBRM1ALDH1A1TDP1L3MBTL1ATM
SCHEMBL12425096 0.86 MEN1 (0.67) PBRM1ALDH1A1TDP1L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110305025-B Method for synthesizing benzylamine compound by imine catalytic hydrogenation 衢州学院 2022-05-06 CN disclosed