Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2872017 | 0.91 | CHRNB2 (0.39) | USP2TSHRCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL2874628 | 0.87 | USP2 (0.44) | USP2TSHRCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL2871693 | 0.87 | HDAC7 (0.39) | USP2TSHRCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL2877735 | 0.85 | CHRNB2 (0.39) | USP2TSHRCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL2874910 | 0.82 | CHRNB2 (0.37) | USP2TSHRCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL2868143 | 0.81 | CHRNB2 (0.36) | USP2TSHRCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL2871472 | 0.81 | CHRNB2 (0.41) | USP2TSHRCHRNB2CHRNB4CHRNA4 | |
| SCHEMBL2874830 | 0.80 | TSHR (0.47) | USP2TSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL2877915 | 0.80 | CHRNB2 (0.39) | CHRNB2CHRNB4CHRNA4CHRNA3HDAC4 | |
| SCHEMBL2877517 | 0.76 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA4CHRNA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | disclosed |