Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 5/20 | 0.33 |
| ▸ | ACE | P12821 | 3/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2871458 | 0.90 | USP2 (0.37) | TSHRUSP2MMEACEALDH1A1 | |
| SCHEMBL2880149 | 0.85 | HDAC7 (0.42) | TSHRUSP2CA1CA2 | |
| SCHEMBL2872456 | 0.85 | TSHR (0.44) | TSHRUSP2MMEACECPA1 | |
| SCHEMBL2875388 | 0.83 | ALDH1A1 (0.33) | TSHRUSP2MMEACEALDH1A1 | |
| SCHEMBL13472634 | 0.82 | TSHR (0.48) | TSHRUSP2ALDH1A1KMT2ACA1 | |
| SCHEMBL2874709 | 0.80 | USP2 (0.47) | TSHRUSP2ALDH1A1MEN1KMT2A | |
| SCHEMBL2875116 | 0.80 | FOLH1 (0.37) | ALDH1A1 | |
| SCHEMBL2871527 | 0.79 | FOLH1 (0.39) | ALDH1A1 | |
| SCHEMBL2874052 | 0.78 | ALDH1A1 (0.35) | TSHRUSP2ALDH1A1MAPT | |
| SCHEMBL2874714 | 0.78 | ACE (0.34) | ACEALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | claimed |
| EP-1570835-B1 | Composition for the permanent deformation of the hair comprising at least one carboxydithiol | OREAL (FR) | 2010-10-20 | — | — | EP | disclosed |