Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.56 |
| ▸ | MMP3 | P08254 | 10/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | PTGES | O14684 | 3/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | GRK5 | P34947 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGFR | P43088 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4445391 | 0.81 | TAAR1 (0.56) | EPHX1PPARGPPARAHDAC1HDAC8 | |
| SCHEMBL5553560 | 0.81 | TAAR1 (0.47) | EPHX1PPARGPPARAHDAC1HDAC8 | |
| SCHEMBL473644 | 0.80 | MMP2 (0.61) | MMP2MMP3PTGESALOX5PPARG | |
| SCHEMBL3467260 | 0.78 | MMP2 (0.60) | MMP2MMP3HDAC1HDAC8S1PR5 | |
| SCHEMBL11360753 | 0.78 | HDAC1 (0.56) | EPHX1PPARGPPARAHDAC1HDAC8 | |
| SCHEMBL27667672 | 0.78 | TAAR1 (0.53) | EPHX1PPARGPPARAHDAC1HDAC8 | |
| SCHEMBL5558144 | 0.78 | THRB (0.51) | EPHX1PPARGPPARAHDAC1HDAC8 | |
| SCHEMBL4990020 | 0.77 | TAAR1 (0.47) | MMP2MMP3EPHX1PPARGPPARA | |
| SCHEMBL4986177 | 0.77 | TAAR1 (0.47) | MMP2MMP3EPHX1PPARGPPARA | |
| SCHEMBL256694 | 0.77 | TAAR1 (0.62) | EPHX1HDAC1HDAC8TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1443187-A | Fused ring modulators of nuclear hormone receptor function | BRISTOL MYERS SQUIBB CO (US) | 2003-09-17 | — | — | CN | disclosed |