Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.57 |
| ▸ | CES1 | P23141 | 2/20 | 0.57 |
| ▸ | PARP1 | P09874 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3269025 | 0.85 | CES2 (0.61) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL29281060 | 0.83 | CES2 (0.59) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL28075891 | 0.81 | CES2 (0.57) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL8400060 | 0.81 | PARP1 (0.58) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL28238806 | 0.80 | CES2 (0.56) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL11751597 | 0.79 | CES2 (0.68) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL27243732 | 0.79 | CES2 (0.68) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL11753938 | 0.77 | CES2 (0.61) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL27713890 | 0.77 | CES2 (0.53) | CES2CES1PARP1HDAC1HDAC6 | |
| SCHEMBL27974641 | 0.77 | CES2 (0.53) | CES2CES1PARP1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1447797-A | New process for preparing quinolone-carboxylic acid | DALIAN LYNCHEM CO LTD (CN) | 2003-10-08 | — | — | CN | disclosed |