Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 5/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.31 |
| ▸ | CDK2 | P24941 | 3/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905776 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27576990 | 0.80 | CDK2 (0.41) | HSP90AA1HSP90AB1CCNE1CDK2CDK1 | |
| SCHEMBL3291053 | 0.79 | KDM4E (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14138147 | 0.77 | HDAC6 (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2914353 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL14642669 | 0.73 | CDK1 (0.56) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2942557 | 0.72 | KDM4E (0.42) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6950568 | 0.72 | ALDH1A1 (0.62) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2914357 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL2942561 | 0.71 | HSP90AA1 (0.45) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100347185-C | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCE CO LTD (KR) | 2007-11-07 | — | — | CN | claimed |
| CN-1487949-A | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | ��ʽ����LG������ѧ | 2004-04-07 | — | — | CN | claimed |
| CN-1921867-B | Nucleoside phosphonate derivatives for the treatment of HIV infection | LG LIFE SCIENCES LTD | 2010-05-05 | — | — | CN | disclosed |
| CN-100347185-C | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCE CO LTD (KR) | 2007-11-07 | — | — | CN | disclosed |
| CN-1487949-A | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | ��ʽ����LG������ѧ | 2004-04-07 | — | — | CN | disclosed |