Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749419 | 1.00 | ACACB (0.50) | ACACBSMN1; SMN2MEN1KMT2AF7 | |
| SCHEMBL23163538 | 0.92 | RXRB (0.55) | ACACBSMN1; SMN2F7RAB9ANPC1 | |
| SCHEMBL23163540 | 0.92 | RXRB (0.55) | ACACBSMN1; SMN2F7RAB9ANPC1 | |
| SCHEMBL27078197 | 0.92 | ALDH1A1 (0.49) | ACACBSMN1; SMN2MEN1KMT2AF7 | |
| SCHEMBL27078201 | 0.92 | ALDH1A1 (0.49) | ACACBSMN1; SMN2MEN1KMT2AF7 | |
| SCHEMBL23163484 | 0.90 | ACACB (0.48) | ACACBSMN1; SMN2MEN1KMT2AF7 | |
| SCHEMBL23163486 | 0.90 | ACACB (0.48) | ACACBSMN1; SMN2MEN1KMT2AF7 | |
| SCHEMBL23163958 | 0.84 | RXRA (0.52) | ACACBSMN1; SMN2KMT2AF7RAB9A | |
| SCHEMBL23163961 | 0.84 | RXRA (0.52) | ACACBSMN1; SMN2KMT2AF7RAB9A | |
| SCHEMBL27078182 | 0.83 | ACACB (0.48) | ACACBSMN1; SMN2ACACANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114555573-A | Prostaglandin E2(PGE2)EP4Receptor antagonists | 多曼治疗学公司 | 2022-05-27 | — | — | CN | disclosed |