Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 13/20 | 0.69 |
| ▸ | HTR1A | P08908 | 6/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.68 |
| ▸ | MAOA | P21397 | 3/20 | 0.66 |
| ▸ | MAOB | P27338 | 3/20 | 0.66 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173130 | 0.80 | NISCH (0.78) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3169242 | 0.79 | NISCH (0.68) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3168567 | 0.76 | NISCH (0.73) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3176645 | 0.73 | ADRA1A (1.00) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3170348 | 0.73 | NISCH (0.62) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Cirazoline SCHEMBL126496 | 0.72 | NISCH (1.00) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL11669738 | 0.72 | NISCH (0.75) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Fenoxazoline SCHEMBL193061 | 0.72 | NISCH (1.00) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Cirazoline SCHEMBL29430417 | 0.72 | NISCH (1.00) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3179178 | 0.72 | ADRA1A (0.64) | NISCHHTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1374967-A | Compounds for the treatment of ischemia | PFIZER PROD INC (US) | 2002-10-16 | — | — | CN | disclosed |