Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 12/20 | 1.00 |
| ▸ | HTR1A | P08908 | 4/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.63 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.63 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.63 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.60 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.60 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | MAOB | P27338 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | THPO | P40225 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenoxazoline SCHEMBL1650113 | 0.99 | NISCH (0.97) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Fenoxazoline SCHEMBL317133 | 0.99 | NISCH (0.97) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Tymazoline SCHEMBL28142132 | 0.90 | NISCH (0.81) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Fenoxazoline SCHEMBL28086604 | 0.86 | NISCH (0.74) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Tymazoline SCHEMBL29387735 | 0.82 | NISCH (0.70) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Tymazoline SCHEMBL250491 | 0.82 | NISCH (0.70) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| Tymazoline SCHEMBL4415590 | 0.81 | NISCH (0.68) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3168567 | 0.81 | NISCH (0.73) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL3169242 | 0.78 | NISCH (0.68) | NISCHHTR1AADRA2AADRA2BADRA2C | |
| SCHEMBL546268 | 0.75 | NISCH (0.78) | NISCHHTR1AADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 802 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114500226-A | HTTP response failover in HTTP scenarios on ICN | IDAC控股公司 | 2022-05-13 | — | — | CN | claimed |
| EP-3331650-B1 | METHOD OF MANUFACTURING A VIBRATABLE HEAD FOR AN AEROSOL GENERATOR AND VIBRATABLE HEAD FOR AN AEROSOL GENERATOR | PARI PHARMA GMBH (DE) | 2020-09-30 | — | — | EP | claimed |
| US-20170196904-A1 | SILICONE OIL-CONTAINING FORMULATIONS FOR NASAL APPLICATION | INQPHARM GROUP SDN BHD (DE) | 2017-07-13 | — | — | US | claimed |
| CN-106659734-A | Silicone oil-containing formulations for nasal application | INQ制药集团有限公司 | 2017-05-10 | — | — | CN | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| EP-2731606-A1 | GEL COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE | Allergan, Inc. (US) | 2014-05-21 | — | — | EP | claimed |
| CN-103796652-A | Gel compositions of oxymetazoline and methods of use | ALLERGAN INC | 2014-05-14 | — | — | CN | claimed |
| US-20130079379-A1 | GEL COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE | ALLERGAN, INC. (US) | 2013-03-28 | — | — | US | claimed |
| WO-2013028909-A1 | COMBINATION THERAPY FOR THE TREATMENT OF SLEEP-RELATED BREATHING DISORDERS | SOVA PHARMACEUTICALS, INC. (US) | 2013-02-28 | — | — | WO | claimed |
| WO-2013010032-A1 | GEL COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE | ALLERGAN, INC. (US) | 2013-01-17 | — | — | WO | claimed |
| EP-0903151-A1 | Use of combinations comprising non-sedating antihistamines and alpha-adrenergic drugs for the topical treatment of rhinitis/conjunctivitis and cold, cold-like and/or flu symptoms | ASTA Medica Aktiengesellschaft (DE) | 1999-03-24 | — | — | EP | claimed |
| EP-0550921-B1 | Pharmaceutical composition for ophthalmic use comprising a nonsteroidal anti-inflammatory and a decongestant drug | ZAMBON SPA (IT) | 1999-03-17 | — | — | EP | claimed |
| US-5334138-A | Drug delivery; mixture of active material and vasoconstrictor | NORTH CAROLINA STATE UNIVERSITY (US) | 1994-08-02 | — | — | US | claimed |
| EP-0448299-B1 | Composition for increased skin concentration of active agents by iontophoresis | BECTON DICKINSON CO (US) | 1994-06-01 | — | — | EP | claimed |
| EP-0550921-A1 | Pharmaceutical composition for ophthalmic use comprising a nonsteroidal anti-inflammatory and a decongestant drug | ZAMBON GROUP S.p.A. (IT) | 1993-07-14 | — | — | EP | claimed |
| EP-0276761-B1 | LATCH DEVICE FOR INCLINABLE BACK REST CUSHION MOUNTED IN SEATBACK | Ikeda Bussan Co., Ltd. (JP) | 1992-06-17 | — | — | EP | claimed |
| EP-0487804-A1 | Deflection yoke | THOMSON TUBES & DISPLAYS SA (FR) | 1992-06-03 | — | — | EP | claimed |
| EP-0448299-A2 | Composition for increased skin concentration of active agents by iontophoresis | Becton, Dickinson and Company (US) | 1991-09-25 | — | — | EP | claimed |
| EP-0276761-A2 | Latch device for inclinable back rest cushion mounted in seatback | Ikeda Bussan Co., Ltd. (JP) | 1988-08-03 | — | — | EP | claimed |
| US-4353600-A | Non-linkage type load sensing valve | NISSAN MOTOR CO., LTD. (JP) | 1982-10-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079379-A1 | GEL COMPOSITIONS OF OXYMETAZOLINE AND METHODS OF USE | CUTA, PDE3A, PTGIS | NISCH 586/4885HTR1A 622/4885ADRA2A 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.