SCHEMBL287503

SCHEMBL287503

CC1CC(C)(C)c2cccc(NC(=O)c3cccnc3)c21

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.50
▸ HTT P42858 2/20 0.50
▸ L3MBTL1 Q9Y468 2/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ MAPT P10636 2/20 0.49
▸ HDAC1 Q13547 3/20 0.49
▸ HDAC3 O15379 1/20 0.49
▸ HDAC2 Q92769 1/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.46
▸ KDM4E B2RXH2 2/20 0.46
▸ TSHR P16473 2/20 0.46
▸ POLB P06746 1/20 0.46
▸ LMNA P02545 1/20 0.45
▸ HIF1A Q16665 1/20 0.45
▸ TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29859557 1.00 ALDH1A1 (0.50) ALDH1A1HTTL3MBTL1ALOX15MAPT
SCHEMBL29504072 0.86 TP53 (0.47) ALDH1A1HTTL3MBTL1ALOX15MAPT
SCHEMBL29613030 0.86 MAPT (0.54) ALDH1A1MAPTHDAC1HDAC3HDAC2
SCHEMBL19666628 0.84 TP53 (0.46) ALDH1A1HTTL3MBTL1ALOX15MAPT
SCHEMBL29587357 0.83 ALDH1A1 (0.45) ALDH1A1HTTL3MBTL1ALOX15MAPT
SCHEMBL16403342 0.82 ALDH1A1 (0.48) ALDH1A1HTTMAPTLMNA
SCHEMBL13278537 0.82 ALDH1A1 (0.48) ALDH1A1HTTMAPTLMNA
SCHEMBL16722767 0.82 ALDH1A1 (0.48) ALDH1A1HTTMAPTLMNA
SCHEMBL12610835 0.81 ALDH1A1 (0.47) ALDH1A1MAPTSMN1; SMN2LMNA
SCHEMBL21063351 0.81 ALDH1A1 (0.47) ALDH1A1MAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120094834-A1 method for increasing the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure BASF SE (DE) 2012-04-19 — — US claimed
JP-4108774-A — — None — — JP disclosed
US-10092008-B2 Method for increasing the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure BAYER CROPSCIENCE LP (US) 2018-10-09 — — US disclosed
US-20160227788-A1 Method for Increasing the Vigor and/or Crop Yield of Agricultural Plants Under Essentially Non-Existent Pathogen Pressure BAYER CROPSCIENCE LP 2016-08-11 — — US disclosed
US-20120094834-A1 method for increasing the vigor and/or crop yield of agricultural plants under essentially non-existent pathogen pressure BASF SE (DE) 2012-04-19 — — US disclosed
EP-2427062-A2 A METHOD FOR INCREASING THE VIGOR AND/OR CROP YIELD OF AGRICULTURAL PLANTS UNDER ESSENTIALLY NON-EXISTENT PATHOGEN PRESSURE BASF SE (DE) 2012-03-14 — — EP disclosed
US-20110318470-A1 Method For Improving Plant Health BASF SE (DE) 2011-12-29 — — US disclosed
EP-2348841-A1 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2011-08-03 — — EP disclosed
WO-2010128003-A2 A METHOD FOR INCREASING THE VIGOR AND/OR CROP YIELD OF AGRICULTURAL PLANTS UNDER ESSENTIALLY NON-EXISTENT PATHOGEN PRESSURE BASF SE (DE) 2010-11-11 — — WO disclosed
WO-2010049414-A1 METHOD FOR IMPROVING PLANT HEALTH BASF SE (DE) 2010-05-06 — — WO disclosed
EP-2096921-A1 AZOLYLMETHYLOXIRANES, THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI, AND COMPOSITIONS COMPRISING THEM BASF SE (DE) 2009-09-09 — — EP disclosed
WO-2009080192-A1 METHOD OF EXAMINING THE AUTHENTICITY OF PLANT PROTECTION AGENTS BY MEANS OF ISOTOPES BAYER CROPSCIENCE AG (DE) 2009-07-02 — — WO disclosed
EP-2048945-A2 NEW MICROEMULSIFIABLE CONCENTRATES Bayer CropScience AG (DE) 2009-04-22 — — EP disclosed
WO-2008155026-A2 ACTIVE INGREDIENT SUSPENSIONS IN GLYCERINE BAYER CROPSCIENCE AG (DE) 2008-12-24 — — WO disclosed
WO-2008089890-A2 OIL SUSPENSION CONCENTRATE WITH MICRO-ENCAPSULATED AGROCHEMICAL ACTIVE INGREDIENTS BAYER CROPSCIENCE AG (DE) 2008-07-31 — — WO disclosed
WO-2008077724-A1 AZOLYLMETHYLOXIRANES, THEIR USE FOR CONTROLLING PHYTOPATHOGENIC FUNGI, AND COMPOSITIONS COMPRISING THEM BASF SE (DE) 2008-07-03 — — WO disclosed
WO-2008074408-A2 PENETRATION ENHANCER FOR FUNGICIDES BAYER CROPSCIENCE AG (DE) 2008-06-26 — — WO disclosed
WO-2008046856-A2 FUNGICIDAL COMPOSITIONS BASF SE (DE) 2008-04-24 — — WO disclosed
WO-2008017378-A2 NEW MICROEMULSIFIABLE CONCENTRATES BAYER CROPSCIENCE AG (DE) 2008-02-14 — — WO disclosed
JP-H04108774-A OPTICALLY ACTIVE N-INDANYLNICOTINIC ACID AMIDE DERIVATIVE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE COMPRISING THE SAME DERIVATIVE AS ACTIVE INGREDIENT MITSUBISHI KASEI CORP 1992-04-09 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110318470-A1 Method For Improving Plant Health BROX, PAH, GUSB ALDH1A1 463/4885HTT 1062/4885L3MBTL1 2008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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