Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593507 | 0.82 | CHRM2 (0.39) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27593641 | 0.79 | ALDH1A1 (0.39) | KDM4EKMT2AALDH1A1USP2MAPT | |
| SCHEMBL27788104 | 0.79 | CHRM2 (0.50) | KDM4EAPAF1MITFTSHRSMN1; SMN2 | |
| SCHEMBL27679806 | 0.78 | CHRM2 (0.40) | KDM4EKMT2AALDH1A1TSHRLMNA | |
| SCHEMBL27845916 | 0.76 | SMN1; SMN2 (0.40) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27718942 | 0.74 | KDM4E (0.43) | KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL27951598 | 0.73 | CHRM2 (0.36) | KDM4EMEN1KMT2AALDH1A1USP2 | |
| SCHEMBL4759272 | 0.73 | KMT2A (0.78) | L3MBTL1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28813536 | 0.73 | ALDH1A1 (0.36) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL27605812 | 0.72 | PARG (0.40) | APAF1MITFMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1462268-A | Substituted cinnamic acid guanidides, method for the production thereof, their use as medicament, and medicine containing these compounds | AVENTIS PHARMA GMBH (DE) | 2003-12-17 | — | — | CN | disclosed |