Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27580962 | 0.93 | ALDH1A1 (0.33) | TRPV4ALDH1A1HPGDSTAT3NPC1 | |
| SCHEMBL27598580 | 0.89 | ALDH1A1 (0.31) | ALDH1A1HPGDSTAT3NPC1RAB9A | |
| SCHEMBL27598408 | 0.87 | MAPT (0.35) | TRPV4HPGDNPC1RAB9AKMT2A | |
| SCHEMBL27598407 | 0.83 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL28751612 | 0.83 | ALDH1A1 (0.34) | TRPV4ALDH1A1HPGDSTAT3NPC1 | |
| SCHEMBL27598409 | 0.82 | MAPT (0.33) | TRPV4ALDH1A1HPGDSTAT3NPC1 | |
| SCHEMBL27581118 | 0.75 | RXFP1 (0.35) | TRPV4ALDH1A1HPGDSTAT3NPC1 | |
| SCHEMBL27598402 | 0.73 | MEN1 (0.39) | TRPV4ALDH1A1HPGDSTAT3KMT2A | |
| SCHEMBL27581054 | 0.72 | TRPV4 (0.34) | TRPV4KMT2AMAPTTP53 | |
| SCHEMBL27580984 | 0.70 | TRPV4 (0.35) | TRPV4ALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1478075-A | Chemical process and new intermediates | ��ŵ�Ѻϳ�ʵ���� | 2004-02-25 | — | — | CN | disclosed |