Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTMT1 | Q9BV86 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2876358 | 0.88 | POLB (0.40) | NTMT1F2RPOLB | |
| SCHEMBL2879577 | 0.82 | GPR88 (0.33) | POLB | |
| SCHEMBL2871091 | 0.80 | IKBKB (0.45) | POLB | |
| SCHEMBL5029771 | 0.80 | IKBKB (0.45) | POLB | |
| SCHEMBL2871093 | 0.80 | IKBKB (0.45) | POLB | |
| SCHEMBL2158312 | 0.80 | KDM4E (0.43) | POLB | |
| SCHEMBL2158314 | 0.80 | KDM4E (0.43) | POLB | |
| SCHEMBL2879446 | 0.79 | GRM5 (0.36) | POLB | |
| SCHEMBL14505565 | 0.76 | IKBKB (0.39) | — | |
| SCHEMBL5436782 | 0.76 | HPGD (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569929-B9 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2011-09-14 | — | — | EP | claimed |
| EP-1569929-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTIONS | VIROCHEM PHARMA INC (CA) | 2010-05-05 | — | — | EP | claimed |