Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.69 |
| ▸ | NAAA | Q02083 | 2/20 | 0.59 |
| ▸ | PTAFR | P25105 | 3/20 | 0.57 |
| ▸ | FES | P07332 | 1/20 | 0.56 |
| ▸ | RET | P07949 | 1/20 | 0.56 |
| ▸ | MARK3 | P27448 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.56 |
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | CLK2 | P49760 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27619602 | 0.89 | TRPV1 (0.57) | TRPV1NAAAPTAFRFESRET | |
| SCHEMBL27619596 | 0.87 | NAAA (0.74) | NAAAALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL6718542 | 0.86 | NAAA (0.73) | NAAAALDH1A1L3MBTL1 | |
| SCHEMBL5045529 | 0.84 | TRPV1 (0.60) | TRPV1NAAAPTAFRLMNAGAA | |
| SCHEMBL1853667 | 0.83 | TRPV1 (0.59) | TRPV1NAAAPTAFR | |
| SCHEMBL5044262 | 0.81 | L3MBTL1 (0.62) | NAAAALDH1A1MAPTL3MBTL1 | |
| SCHEMBL25330125 | 0.81 | NAAA (0.68) | NAAALMNA | |
| SCHEMBL2356495 | 0.81 | NAAA (0.68) | NAAALMNA | |
| SCHEMBL9763677 | 0.81 | NAAA (0.68) | NAAALMNA | |
| SCHEMBL5694314 | 0.81 | NAAA (0.68) | NAAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |