Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1856563 | 0.78 | TSHR (0.54) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL4715407 | 0.77 | SMN1; SMN2 (0.69) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL4715831 | 0.76 | TSHR (0.60) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL1853154 | 0.75 | KMT2A (0.66) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL4714622 | 0.73 | TSHR (0.56) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL1856043 | 0.73 | SMN1; SMN2 (0.56) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL5048888 | 0.72 | SMN1; SMN2 (0.53) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL4715815 | 0.70 | KMT2A (0.71) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL1856431 | 0.70 | SMN1; SMN2 (0.50) | KMT2ASMN1; SMN2MEN1HTTTSHR | |
| SCHEMBL1854872 | 0.70 | KMT2A (0.55) | KMT2ASMN1; SMN2MEN1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100410236-C | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (CH) | 2008-08-13 | — | — | CN | disclosed |
| CN-1633410-A | Substituted methylene amide derivatives as protein tyrosine phosphatase modulators | APPLIED RESEARCH SYSTEMS (AN) | 2005-06-29 | — | — | CN | disclosed |