Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667002 | 0.86 | MTNR1A (0.59) | MTNR1ATRPV1MTNR1BNQO2 | |
| SCHEMBL5095627 | 0.80 | ESR1 (0.69) | MTNR1AESR1ESR2TRPV1MTNR1B | |
| SCHEMBL5101693 | 0.79 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7355324 | 0.76 | MTNR1A (0.48) | MTNR1ATRPV1MTNR1BNQO2KMT2A | |
| SCHEMBL11569727 | 0.74 | ESR1 (0.62) | ESR1ESR2 | |
| SCHEMBL2384355 | 0.73 | PTGS1 (0.53) | KMT2ALOXL2 | |
| SCHEMBL2667112 | 0.72 | MTNR1A (0.48) | MTNR1AESR1ESR2TRPV1MTNR1B | |
| SCHEMBL5397777 | 0.71 | MTNR1A (0.62) | MTNR1ATRPV1MTNR1BNQO2 | |
| SCHEMBL22652430 | 0.71 | KMT2A (0.41) | MTNR1AMTNR1BNQO2KMT2ALMNA | |
| SCHEMBL7456002 | 0.71 | KMT2A (0.44) | MTNR1ATRPV1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975583-B1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | MERIAL LTD (US) | 2010-10-20 | — | — | EP | disclosed |
| US-6555709-B1 | Derivatives of 4-(naphth-2-ylmethyl)-N-(2-methylphenyl) benzamide; storing crops (cotton and rice); insecticides; miticides; nematocides; molluscs; anthelmintics; acarina; textiles; foods | HOECHST SCHERING AGREVO S.A. (FR) | 2003-04-29 | — | — | US | disclosed |
| EP-0975583-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo S.A. (FR) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998045252-A1 | AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO S.A. (FR) | 1998-10-15 | — | — | WO | disclosed |