Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389496 | 0.73 | SLC6A3 (0.49) | LMNASLC6A3SLC6A2SLC6A4TDP1 | |
| SCHEMBL7001903 | 0.72 | NPC1 (0.54) | LMNATSHRTAAR1IDO1 | |
| SCHEMBL8703610 | 0.71 | TAAR1 (0.64) | TSHRTAAR1IDO1 | |
| SCHEMBL29930048 | 0.71 | TAAR1 (0.64) | TSHRTAAR1IDO1 | |
| SCHEMBL28752735 | 0.70 | EPHX2 (0.50) | LMNASLC6A3SLC6A2SLC6A4TAAR1 | |
| SCHEMBL27605819 | 0.69 | TAAR1 (0.42) | MAPTTSHRTAAR1IDO1 | |
| SCHEMBL4758082 | 0.68 | ADRA1D (0.51) | LMNAMAPTTSHRHTTSLC6A3 | |
| SCHEMBL9710124 | 0.67 | CYP3A4 (0.48) | TSHRSLC6A3SLC6A2TDP1ADCY10 | |
| SCHEMBL28550049 | 0.66 | KMT2A (0.47) | MAPTTSHRTAAR1IDO1 | |
| SCHEMBL23223243 | 0.66 | SLC6A3 (0.43) | SLC6A3SLC6A2IDO1ADCY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100593401-C | Combination of an aromatase inhibitor with a bisphosphonate | NOVARTIS AG | 2010-03-10 | — | — | CN | disclosed |
| CN-100377710-C | Aromatase inhibition to enhance assisted reproduction | ARES TRADE INC (CH) | 2008-04-02 | — | — | CN | disclosed |
| CN-1671371-A | Combination of an aromatase inhibitor with a bisphosphonate | NOVARTIS AG (CH) | 2005-09-21 | — | — | CN | disclosed |
| CN-1551789-A | Single dose aromatase inhibitor for treating infertility | ����˹ó�ɷ�����˾ | 2004-12-01 | — | — | CN | disclosed |
| CN-1549734-A | Aromatase inhibitors for enhancing assisted reproduction | ����˹ó�ɷ�����˾ | 2004-11-24 | — | — | CN | disclosed |