Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 9/20 | 1.00 |
| ▸ | TUBB | P07437 | 9/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 9/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 9/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 9/20 | 1.00 |
| ▸ | TUBB4B | P68371 | 9/20 | 1.00 |
| ▸ | TUBB3 | Q13509 | 9/20 | 1.00 |
| ▸ | TUBB2A | Q13885 | 9/20 | 1.00 |
| ▸ | TUBB8 | Q3ZCM7 | 9/20 | 1.00 |
| ▸ | TUBA3E | Q6PEY2 | 9/20 | 1.00 |
| ▸ | TUBA1A | Q71U36 | 9/20 | 1.00 |
| ▸ | TUBA1C | Q9BQE3 | 9/20 | 1.00 |
| ▸ | TUBB6 | Q9BUF5 | 9/20 | 1.00 |
| ▸ | TUBB2B | Q9BVA1 | 9/20 | 1.00 |
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 0.81 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30785779 | 1.00 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28753130 | 0.95 | TUBB4A (0.91) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29511469 | 0.95 | TUBB4A (0.91) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28753100 | 0.93 | TUBB4A (0.88) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28753115 | 0.93 | TUBB4A (0.88) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30785776 | 0.93 | TUBB4A (0.88) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30785778 | 0.93 | TUBB4A (0.88) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28941813 | 0.92 | TUBB4A (0.86) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL28753241 | 0.91 | TUBB4A (0.84) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| Parbendazole SCHEMBL259456 | 0.90 | TUBB4A (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436972-A | Pabendazole derivative and preparation method and application thereof | 山东大学 | 2022-05-06 | — | — | CN | claimed |
| CN-114436972-B | Pabendazole derivative, and preparation method and application thereof | 山东大学 | 2024-02-13 | — | — | CN | disclosed |
| CN-114436972-A | Pabendazole derivative and preparation method and application thereof | 山东大学 | 2022-05-06 | — | — | CN | disclosed |