Parbendazole

Parbendazole

SCHEMBL259456

CCCCc1ccc2nc(NC(=O)OC)[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 8/20 1.00
TUBB P07437 8/20 1.00
TUBA3C P0DPH7 8/20 1.00
TUBA1B P68363 8/20 1.00
TUBA4A P68366 8/20 1.00
TUBB4B P68371 8/20 1.00
TUBB3 Q13509 8/20 1.00
TUBB2A Q13885 8/20 1.00
TUBB8 Q3ZCM7 8/20 1.00
TUBA3E Q6PEY2 8/20 1.00
TUBA1A Q71U36 8/20 1.00
TUBA1C Q9BQE3 8/20 1.00
TUBB6 Q9BUF5 8/20 1.00
TUBB2B Q9BVA1 8/20 1.00
TUBB1 Q9H4B7 8/20 1.00
LMNA P02545 7/20 1.00
CYP1A2 P05177 5/20 1.00
HIF1A Q16665 4/20 1.00
CYP2D6 P10635 1/20 1.00
TSHR P16473 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Parbendazole SCHEMBL27363030 1.00 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Parbendazole SCHEMBL259455 0.90 TUBB4A (0.82) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
Parbendazole SCHEMBL29409286 0.90 TUBB4A (0.82) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28753124 0.90 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29511469 0.90 TUBB4A (0.91) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28753130 0.90 TUBB4A (0.91) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL30785779 0.90 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL28753108 0.89 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL29511339 0.89 TUBB4A (1.00) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL11212646 0.88 TUBB4A (0.78) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3365 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676479-A1 PARBENDAZOLE FOR USE IN THE TREATMENT OF DEMENTIA Trustlife Global Inc. (US) 2026-01-14 EP claimed
US-20250352518-A1 A BENZIMIDAZOLE COMPOUND WITH ANTIHELMINTHIC ACTIVITY FOR USE IN REVERSING, ARRESTING OR SLOWING DOWN CELLULAR AGEING IN A VERTEBRATE SUBJECT RAVAN BIO LIMITED (GB) 2025-11-20 US claimed
EP-4615576-A1 CELLS BEING HIGHLY ENRICHED IN SASP FACTORS, AND COMPOSITION COMPRISING SAID CELLS Evomedis GmbH (AT) 2025-09-17 EP claimed
US-20250262167-A1 COMPOUNDS, TARGETS AND PATHWAYS FOR MACROPHAGE MODULATION MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2025-08-21 US claimed
EP-4586826-A1 FEED AND METHODS FOR CONTROLLING HEARTWORM INFECTIONS IN A MAMMAL In the Bowl Animal Health, Inc. (US) 2025-07-23 EP claimed
EP-4539808-A1 A BENZIMIDAZOLE COMPOUND WITH ANTIHELMINTHIC ACTIVITY FOR USE IN REVERSING, ARRESTING OR SLOWING DOWN CELLULAR AGEING IN A VERTEBRATE SUBJECT Ravan Bio Limited (GB) 2025-04-23 EP claimed
US-20250114393-A1 CANCER TREATMENT REGIMEN USING ANTI-PARASITIC COMPOUNDS AND GUT MICROBIOME MODULATING AGENTS FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES 2025-04-10 US claimed
US-12194058-B2 Cancer treatment regimen using anti-parasitic compounds and gut microbiome modulating agents FLORIDA ATLANTIC UNIVERSITY BOARD OF TRUSTEES (US) 2025-01-14 US claimed
US-20240352429-A1 AGENT FOR INDUCING VIRAL VECTOR PRODUCTION KANEKA CORPORATION (JP) 2024-10-24 US claimed
WO-2024184532-A1 PARBENDAZOLE FOR USE IN THE TREATMENT OF DEMENTIA BASH BIOTECH INC (US) 2024-09-12 WO claimed
EP-0202568-A1 Anthelmintic compositions SYNTEX (U.S.A.) INC. (US) 1986-11-26 EP claimed
EP-0146556-A4 POTENTIATION OF ANTHELMINTICS. COMMW SCIENT IND RES ORG (AU) 1985-09-16 EP claimed
EP-0146573-A1 PHARMACEUTICAL COMPOSITIONS WITH ANTHELMINTIC ACTIVITY, DOSAGE UNITS THEREOF AND METHOD FOR TREATING HELMINTHIASIS IN ANIMALS HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-03 EP claimed
EP-0146556-A1 POTENTIATION OF ANTHELMINTICS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1985-07-03 EP claimed
WO-1984004677-A1 PHARMACEUTICAL COMPOSITIONS WITH ANTHELMINTIC ACTIVITY, DOSAGE UNITS THEREOF AND METHOD FOR TREATING HELMINTHIASIS IN ANIMALS HOECHST AG (DE) 1984-12-06 WO claimed
WO-1984004455-A1 POTENTIATION OF ANTHELMINTICS COMMW SCIENT IND RES ORG (AU) 1984-11-22 WO claimed
EP-0059074-B1 ANTHELMINTIC COMPOSITION AND THE USE THEREOF SANKYO COMPANY LIMITED (JP) 1984-10-10 EP claimed
US-4468390-A Anthelmintic composition and the use thereof SANKYO COMPANY, LIMITED (JP) 1984-08-28 US claimed
EP-0090368-A1 Anthelmintic preparations HOECHST UK LIMITED (GB) 1983-10-05 EP claimed
EP-0059074-A1 Anthelmintic composition and the use thereof SANKYO COMPANY LIMITED (JP) 1982-09-01 EP claimed