Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27464017 | 0.95 | BRD4 (0.30) | — | |
| Hydrochloric Acid SCHEMBL7200620 | 0.91 | BRD4 (0.31) | — | |
| Hydrochloric Acid SCHEMBL27689381 | 0.87 | HSD17B10 (0.38) | — | |
| Hydrochloric Acid SCHEMBL27670356 | 0.87 | KCNH2 (0.34) | KCNH2 | |
| Hydrochloric Acid SCHEMBL27479668 | 0.87 | SOAT1 (0.38) | KCNH2CNR1 | |
| Hydrochloric Acid SCHEMBL27689388 | 0.86 | SLC6A2 (0.33) | KCNH2 | |
| Hydrochloric Acid SCHEMBL27446170 | 0.86 | HSD17B10 (0.37) | — | |
| Hydrochloric Acid SCHEMBL27689398 | 0.86 | HSD17B10 (0.37) | — | |
| Hydrochloric Acid SCHEMBL27670344 | 0.86 | HSD17B10 (0.35) | KCNH2 | |
| Hydrochloric Acid SCHEMBL29695950 | 0.86 | BRD4 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110167973-B | High purity polypropylene for molding and polypropylene composition | 道达尔研究技术弗吕公司 | 2022-06-17 | — | — | CN | disclosed |