Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | BRAF | P15056 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29002168 | 0.81 | MEN1 (0.50) | MEN1KMT2AMAPTABCB1TUBB4A | |
| SCHEMBL5057415 | 0.76 | ALDH1A1 (0.46) | MAPTATMALDH1A1 | |
| SCHEMBL9066195 | 0.73 | CYP1A2 (0.61) | MEN1KMT2AMAPTATMSMN1; SMN2 | |
| SCHEMBL17948239 | 0.73 | MEN1 (0.71) | MEN1KMT2ABRAFMAPTNPC1 | |
| SCHEMBL3631829 | 0.72 | BRAF (0.70) | MEN1KMT2ABRAFSMN1; SMN2TUBB4A | |
| SCHEMBL4910445 | 0.71 | CA1 (0.59) | MAPTSMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL5841124 | 0.71 | BRAF (0.69) | MEN1KMT2ABRAFMAPTATM | |
| SCHEMBL8346193 | 0.70 | ABCG2 (0.57) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL11468589 | 0.70 | KDM4E (0.44) | MEN1KMT2AMAPTSMN1; SMN2TP53 | |
| SCHEMBL26956146 | 0.70 | ALDH1A1 (0.47) | MEN1KMT2AMAPTABCB1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1578663-B | Histone deacetylase inhibitors | METHYLGENE INC | 2011-05-25 | — | — | CN | disclosed |
| CN-1578663-A | Histone deacetylase inhibitors | METHYLGENE INC (CA) | 2005-02-09 | — | — | CN | disclosed |