SCHEMBL4910445

SCHEMBL4910445

C=C(C(=O)OC)c1ccc(OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.59
CA2 P00918 6/20 0.59
MAPT P10636 1/20 0.58
CES2 O00748 2/20 0.57
CES1 P23141 2/20 0.57
PLK1 P53350 1/20 0.55
PARP1 P09874 1/20 0.53
PARP10 Q53GL7 1/20 0.53
PARP2 Q9UGN5 1/20 0.53
PARP4 Q9UKK3 1/20 0.53
NPC1 O15118 1/20 0.52
TP53 P04637 1/20 0.52
ALOX15 P16050 1/20 0.52
RAB9A P51151 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
PKM P14618 1/20 0.49
F10 P00742 1/20 0.49
GSK3B P49841 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5057415 0.89 ALDH1A1 (0.46) CA1CA2MAPTCES2CES1
SCHEMBL22423019 0.89 CA1 (0.60) CA1CA2MAPTCES2CES1
SCHEMBL9301384 0.84 KDM4E (0.62) CA1CA2MAPTNPC1RAB9A
SCHEMBL5378414 0.83 MAPT (0.59) CA1CA2MAPTCES2CES1
SCHEMBL8897038 0.82 PARP10 (0.53) MAPTPARP10NPC1RAB9ASMN1; SMN2
SCHEMBL4224768 0.82 MAPT (0.51) CA1CA2MAPTCES2CES1
SCHEMBL4113521 0.82 HDAC3 (0.53) CA1CA2MAPTCES2CES1
SCHEMBL9300725 0.82 TDP1 (0.57) MAPTCES2CES1NPC1RAB9A
Butane SCHEMBL7720074 0.82 TDP1 (0.41) CA1CA2MAPTPLK1
SCHEMBL562943 0.82 CA1 (0.63) CA1CA2MAPTCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1884364-A Composition for manufacturing photochromic resin lens SHANGHAI WEIXING OPTICAL CO LT (CN) 2006-12-27 CN claimed
WO-2025226510-A1 LPAR1 INHIBITORS ABBVIE INC. (US) 2025-10-30 WO disclosed
EP-4640274-A1 LPAR1 INHIBITORS AbbVie Inc. (US) 2025-10-29 EP disclosed
US-20240287129-A1 DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF THE TRUSTEES OF PRINCETON UNIVERSITY 2024-08-29 US disclosed
US-11981704-B2 Decarboxylative conjugate additions and applications thereof THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2024-05-14 US disclosed
CN-114835738-B Method for preparing allyl borate by using biomass-based catalytic material 湖北工程学院 2023-09-29 CN disclosed
CN-113509961-B Application of chitosan/cellulose composite microsphere immobilized copper in preparation of allylsilane compound 湖北工程学院 2023-05-23 CN disclosed
CN-110903189-B Synthesis method of chiral 2-aryl propionate 大连大学 2022-06-21 CN disclosed
US-20220002342-A1 DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF THE TRUSTEES OF PRINCETON UNIVERSITY 2022-01-06 US disclosed
US-11136349-B2 Decarboxylative conjugate additions and applications thereof THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2021-10-05 US disclosed
CN-1079811-C Polymeric composite material ASAHI CHEMICAL IND (JP) 2002-02-27 CN disclosed
CN-1164250-A Polymeric composite material ASAHI CHEMICAL IND (JP) 1997-11-05 CN disclosed
US-5670531-A ENKEPHALINASE OR ANGIOTENSIN CONVERTING ENZYME INHIBITORS SOCIETE CIVILE BIOPROJET (FR) 1997-09-23 US disclosed
EP-0484122-B1 Method for obtaining high-purity cinnamic acid MITSUI TOATSU CHEMICALS (JP) 1996-01-17 EP disclosed
US-5206430-A METHOD FOR OBTAINING HIGH-PURITY CINNAMIC ACID MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1993-04-27 US disclosed
EP-0484122-A2 Method for obtaining high-purity cinnamic acid MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-05-06 EP disclosed
US-5063225-A Antiarrhythmia ROUSSEL UCLAF (FR) 1991-11-05 US disclosed
EP-0240138-B1 PREPARATION OF CINNAMIC ACIDS MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-09-18 EP disclosed
US-4806683-A Preparation process of cinnamic acids MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-02-21 US disclosed
EP-0240138-A1 Preparation of cinnamic acids MITSUI TOATSU CHEMICALS, Inc. (JP) 1987-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220002342-A1 DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF PTMS, DNPEP, QPCT CA1 598/4885CA2 2519/4885MAPT 3051/4885
US-20240287129-A1 DECARBOXYLATIVE CONJUGATE ADDITIONS AND APPLICATIONS THEREOF PTMS, DNPEP, QPCT CA1 598/4885CA2 2519/4885MAPT 3051/4885
US-11981704-B2 Decarboxylative conjugate additions and applications thereof PTMS, DNPEP, QPCT CA1 598/4885CA2 2519/4885MAPT 3051/4885
US-11136349-B2 Decarboxylative conjugate additions and applications thereof PTMS, DNPEP, QPCT CA1 598/4885CA2 2519/4885MAPT 3051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.