Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 9/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PKLR | P30613 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527999 | 1.00 | ALDH1A1 (0.37) | ALDH1A1ALOX15MALT1MAPTTP53 | |
| SCHEMBL3739493 | 0.84 | ALDH1A1 (0.44) | ALDH1A1ALOX15MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL5353984 | 0.84 | MAPT (0.33) | ALDH1A1MALT1MAPTTP53NPC1 | |
| SCHEMBL3747840 | 0.81 | GAA (0.44) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL18690248 | 0.78 | MAPT (0.34) | ALDH1A1MAPTTP53NPC1RAB9A | |
| SCHEMBL30546824 | 0.78 | MAPT (0.34) | ALDH1A1MAPTTP53NPC1RAB9A | |
| SCHEMBL7555956 | 0.71 | MAPT (0.39) | ALDH1A1ALOX15MAPTTP53NPC1 | |
| SCHEMBL346282 | 0.71 | — | — | |
| SCHEMBL1340900 | 0.70 | ALDH1A1 (0.50) | ALDH1A1ALOX15MAPTKDM4EMEN1 | |
| SCHEMBL10589330 | 0.69 | MAPT (0.38) | ALDH1A1ALOX15MAPTTP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108409684-B | N- (2-cyclohexyloxyphenyl) amide compound and preparation method and application thereof | 上海晓明检测技术服务有限公司 | 2022-04-12 | — | — | CN | disclosed |