Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL562880 | 0.81 | PARP1 (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL29527999 | 0.81 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28754170 | 0.81 | ALDH1A1 (0.37) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5353984 | 0.80 | MAPT (0.33) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3739493 | 0.80 | ALDH1A1 (0.44) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL27623031 | 0.79 | ALDH1A1 (0.40) | GAAKDM4EP2RX7ALDH1A1MAPT | |
| SCHEMBL12391733 | 0.74 | MAPT (0.33) | GAAKDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL30546824 | 0.74 | MAPT (0.34) | KDM4EALDH1A1MAPTGFERMEN1 | |
| SCHEMBL4031502 | 0.74 | GAA (0.44) | GAAKDM4EP2RX7ALDH1A1CTSD | |
| SCHEMBL18690248 | 0.74 | MAPT (0.34) | KDM4EALDH1A1MAPTGFERMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | claimed |
| US-8481810-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-09 | — | — | US | disclosed |
| US-7838732-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-23 | — | — | US | disclosed |
| WO-2009095098-A2 | USE OF BENZOTHIADIAZOLES | RWTH AACHEN (DE) | 2009-08-06 | — | — | WO | disclosed |
| US-7361806-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-22 | — | — | US | disclosed |
| US-20080078005-A1 | TRANSGENIC PLANTS EXPRESSING A CELLULASE | LEBEL EDOUARD G | 2008-03-27 | — | — | US | disclosed |
| US-20080022425-A1 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATION AG | 2008-01-24 | — | — | US | disclosed |
| US-7030294-B2 | Heterologous expression cassette of a nucleotide sequence under control of an inducible promoter | SYNGENTA PARTICIPATIONS AG (CH) | 2006-04-18 | — | — | US | disclosed |
| EP-1574580-A2 | Transgenic plants expressing cellulolytic enzymes | Syngenta Participations AG (CH) | 2005-09-14 | — | — | EP | disclosed |
| EP-0925362-B1 | TRANSGENIC PLANTS EXPRESSING CELLULOLYTIC ENZYMES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-07-20 | — | — | EP | disclosed |
| US-5789214-A | TRANSPORTATION OF PLANT TISSUES, NUCLEIC ACID PROMOTER FRAGMENTS, CODES AND EXPOSING TISSUES | NOVARTIS FINANCE CORPORATION (US) | 1998-08-04 | — | — | US | disclosed |
| US-5777200-A | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof | NOVARTIS FINANCE CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| WO-1998026082-A1 | METHODS OF USING THE NIM1 GENE TO CONFER DISEASE RESISTANCE IN PLANTS | NOVARTIS AG (CH) | 1998-06-18 | — | — | WO | disclosed |
| US-5767369-A | PLANT RESISTANCE | NOVARTIS FINANCE CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |
| WO-1998011235-A2 | TRANSGENIC PLANTS EXPRESSING CELLULOLYTIC ENZYMES | NOVARTIS AG (CH) | 1998-03-19 | — | — | WO | disclosed |
| US-5689044-A | GENETIC ENGINEERING | NOVARTIS CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| US-5654414-A | GENETIC ENGINEERING | NOVARTIS FINANCE CORPORATION (US) | 1997-08-05 | — | — | US | disclosed |
| US-5650505-A | Chemically regulatable and anti-pathogenic DNA sequences and uses thereof | NOVARTIS CORPORATION (US) | 1997-07-22 | — | — | US | disclosed |
| US-5614395-A | SCREENING FOR AGROCHEMICALS HAVING THE ABILITY TO INDUCE SYSTEMIC ACQUIRED RESISTANCE IN PLANTS | CIBA-GEIGY CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | disclosed |