Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.54 |
| ▸ | MIF | P14174 | 8/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9436016 | 0.83 | KDM4E (0.54) | HSD17B3MIFKDM4EMEN1S1PR4 | |
| SCHEMBL29089438 | 0.83 | ADAM17 (0.64) | KDM4EMEN1KMT2APOLBMAOB | |
| SCHEMBL15082511 | 0.82 | HSD17B3 (0.59) | HSD17B3MIFKDM4EMEN1S1PR4 | |
| SCHEMBL30405545 | 0.81 | HSD17B3 (0.65) | HSD17B3MIFKDM4EMEN1S1PR4 | |
| SCHEMBL220708 | 0.81 | HSD17B3 (0.65) | HSD17B3MIFKDM4EMEN1S1PR4 | |
| SCHEMBL15084975 | 0.80 | POLB (0.58) | HSD17B3MIFKDM4EMEN1S1PR4 | |
| SCHEMBL27844746 | 0.80 | GAA (0.58) | HSD17B3MIFKDM4EMEN1S1PR4 | |
| SCHEMBL12433441 | 0.80 | POLB (0.57) | HSD17B3MIFKDM4EMEN1S1PR4 | |
| SCHEMBL28164061 | 0.79 | POLB (0.59) | HSD17B3MIFKDM4EMEN1S1PR4 | |
| SCHEMBL4527127 | 0.79 | HSD17B3 (0.55) | HSD17B3MIFKDM4EMEN1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113527595-B | Functionalized organic silicon resin and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2022-06-07 | — | — | CN | disclosed |
| CN-113527595-A | Functionalized organic silicon resin and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2021-10-22 | — | — | CN | disclosed |