Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.35 |
| ▸ | RELA | Q04206 | 3/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6588593 | 0.82 | CA1 (0.43) | CA12CA14CA2CA1CA7 | |
| SCHEMBL5985561 | 0.78 | CA1 (0.41) | CA12CA14CA2CA1CA7 | |
| SCHEMBL7878490 | 0.76 | CTSK (0.43) | CA12CA14CA2CA1CA7 | |
| SCHEMBL24786835 | 0.75 | CA12 (0.36) | CA12CA14CA2CA1CA7 | |
| SCHEMBL5768258 | 0.73 | CTSK (0.46) | CTSK | |
| SCHEMBL15096829 | 0.72 | MAPK10 (0.41) | CA12CA14CA2CA1CA7 | |
| SCHEMBL12571335 | 0.72 | MAPK10 (0.41) | CA12CA14CA2CA1CA7 | |
| SCHEMBL21426201 | 0.71 | CA1 (0.49) | CA12CA14CA2CA1CA7 | |
| SCHEMBL27111696 | 0.71 | CA1 (0.41) | CA12CA14CA2CA1CA7 | |
| SCHEMBL208785 | 0.70 | CTSK (0.42) | CA12CA14CA2CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114630823-A | GLP-1R modulating compounds | 吉利德科学公司 | 2022-06-14 | — | — | CN | disclosed |