Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332609 | 0.96 | THRB (0.55) | PTGS2ALOX5THRATHRBPPARA | |
| SCHEMBL6682611 | 0.96 | THRB (0.55) | PTGS2ALOX5THRATHRBPPARA | |
| SCHEMBL6681345 | 0.96 | THRB (0.55) | PTGS2ALOX5THRATHRBPPARA | |
| SCHEMBL28214185 | 0.96 | THRB (0.55) | PTGS2ALOX5THRATHRBPPARA | |
| SCHEMBL6441843 | 0.96 | THRB (0.55) | PTGS2ALOX5THRATHRBPPARA | |
| SCHEMBL6686357 | 0.96 | THRB (0.55) | PTGS2ALOX5THRATHRBPPARA | |
| SCHEMBL4059772 | 0.95 | L3MBTL1 (0.55) | PTGS2ALOX5THRATHRBPPARA | |
| SCHEMBL6681802 | 0.93 | L3MBTL1 (0.56) | PTGS2ALOX5THRATHRBMAPT | |
| SCHEMBL11755272 | 0.87 | THRB (0.55) | PTGS2ALOX5THRATHRBPPARA | |
| SCHEMBL11564959 | 0.87 | THRB (0.55) | PTGS2ALOX5THRATHRBPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100359346-C | Photochromic optical article | TRANSITIONS OPTICAL INC (US) | 2008-01-02 | — | — | CN | disclosed |
| CN-1608216-A | Photochromic optical articles | TRANSITIONS OPTICAL INC (US) | 2005-04-20 | — | — | CN | disclosed |