Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urethane SCHEMBL27620983 | 0.92 | MAPT (0.52) | MAPTPOLBMAPK1TDP1MEN1 | |
| SCHEMBL27621055 | 0.88 | MAPT (0.45) | MAPTPOLBMAPK1TDP1MEN1 | |
| SCHEMBL27639789 | 0.88 | MAPT (0.45) | MAPTPOLBMAPK1TDP1MEN1 | |
| SCHEMBL27639797 | 0.88 | MAPT (0.59) | MAPTPOLBMAPK1TDP1MEN1 | |
| SCHEMBL27639776 | 0.87 | ALOX5 (0.57) | MAPTPOLBMAPK1TDP1ALOX5 | |
| SCHEMBL27639794 | 0.87 | PTGDR2 (0.46) | MAPTPOLBMAPK1TDP1MEN1 | |
| SCHEMBL27639760 | 0.85 | MAPT (0.45) | MAPTPOLBMAPK1TDP1MEN1 | |
| Acetamide SCHEMBL27567357 | 0.84 | ALDH1A1 (0.51) | MAPTPOLBMAPK1TDP1KMT2A | |
| SCHEMBL27405553 | 0.84 | ALDH1A1 (0.56) | MAPTPOLBMAPK1TDP1KMT2A | |
| Methyl Alcohol SCHEMBL28251314 | 0.83 | ALDH1A1 (0.55) | MAPTPOLBMAPK1TDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1761464-A | Substituted p-diaminobenzene derivatives | LUNDBECK & CO AS H (DK) | 2006-04-19 | — | — | CN | disclosed |