Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2937142 | 0.76 | HDAC3 (0.37) | RCE1HDAC1HDAC3ESR1ESR2 | |
| SCHEMBL29001417 | 0.75 | MEN1 (0.50) | MMP12MMP13HDAC1HDAC8MMP8 | |
| SCHEMBL27449196 | 0.71 | CYP4A11 (0.41) | MMP12MMP13HDAC1HDAC8ESR1 | |
| SCHEMBL248501 | 0.70 | CA2 (0.53) | MMP12MMP13HSD17B10HDAC1HDAC8 | |
| SCHEMBL28822705 | 0.69 | CA2 (0.52) | MMP12MMP13HDAC1HDAC8HDAC6 | |
| SCHEMBL8145771 | 0.69 | ESR1 (0.56) | HSD17B10ESR1ESR2KMT2A | |
| SCHEMBL9653975 | 0.69 | RECQL (0.41) | MMP12MMP13ESR1ESR2MMP8 | |
| Ammonia Solution, Strong SCHEMBL31358922 | 0.69 | CA2 (0.52) | MMP12MMP13HDAC1HDAC8HDAC6 | |
| Hydrochloric Acid SCHEMBL11371981 | 0.69 | CA2 (0.52) | MMP12MMP13HDAC1HDAC8HDAC6 | |
| Fluoride SCHEMBL27466222 | 0.69 | CA2 (0.52) | MMP12MMP13HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100586485-C | Radiofluorination method of bioactive carrier | AMERSHAM HEALTH AS | 2010-02-03 | — | — | CN | disclosed |
| CN-1758925-A | Radiofluorination method of bioactive carrier | AMERSHAM HEALTH AS (NO) | 2006-04-12 | — | — | CN | disclosed |