SCHEMBL28822705

SCHEMBL28822705

O=S(=O)(O)CCc1ccccc1.[NaH]

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.52
LMNA P02545 2/20 0.52
ALDH1A1 P00352 2/20 0.52
KDM4E B2RXH2 1/20 0.52
CYP3A4 P08684 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
BLM P54132 1/20 0.52
GFER P55789 1/20 0.52
PMP22 Q01453 1/20 0.52
IDO1 P14902 1/20 0.48
MMP12 P39900 2/20 0.47
MMP13 P45452 2/20 0.47
MMP1 P03956 1/20 0.47
MMP7 P09237 1/20 0.47
MMP8 P22894 1/20 0.47
KEAP1 Q14145 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CA1 P00915 2/20 0.44
CA12 O43570 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27711383 1.00 CA2 (0.52) CA2LMNAALDH1A1KDM4ECYP3A4
SCHEMBL248501 0.98 CA2 (0.53) CA2LMNAALDH1A1KDM4ECYP3A4
Fluoride SCHEMBL27466222 0.95 CA2 (0.52) CA2LMNAALDH1A1KDM4ECYP3A4
SCHEMBL27572624 0.95 CA2 (0.52) CA2LMNAALDH1A1KDM4ECYP3A4
Hydrochloric Acid SCHEMBL11371981 0.95 CA2 (0.52) CA2LMNAALDH1A1KDM4ECYP3A4
Ammonia Solution, Strong SCHEMBL31358922 0.95 CA2 (0.52) CA2LMNAALDH1A1KDM4ECYP3A4
SCHEMBL11869687 0.90 KDM4E (0.52) CA2LMNAALDH1A1KDM4ECYP3A4
SCHEMBL31352715 0.86 CA2 (0.49) CA2LMNAALDH1A1KDM4ECYP3A4
SCHEMBL8600793 0.85 MMP12 (0.64) CA2LMNAGAAMMP12MMP13
SCHEMBL249113 0.84 CA2 (0.56) CA2LMNAALDH1A1KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892444-A Method for synthesizing D-p-hydroxyphenylglycine methyl ester SHANXI XINGHUO WEIMIN PHARMACEUTICAL CO LTD 2015-09-09 CN claimed
CN-104892444-A Method for synthesizing D-p-hydroxyphenylglycine methyl ester SHANXI XINGHUO WEIMIN PHARMACEUTICAL CO LTD 2015-09-09 CN disclosed