Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28755192 | 0.88 | GAA (0.60) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28755308 | 0.87 | GAA (0.53) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28603840 | 0.86 | CYP1A1 (0.46) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28603844 | 0.86 | CYP1A1 (0.46) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28755342 | 0.85 | GAA (0.53) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28755329 | 0.83 | KMT2A (0.60) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28755189 | 0.83 | GAA (0.56) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28755330 | 0.83 | GAA (0.56) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28755304 | 0.80 | GAA (0.56) | GAAMAPTLMNAHPGDTSHR | |
| SCHEMBL28755281 | 0.78 | GAA (0.51) | GAAMAPTLMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107382899-B | Polysubstituted 2-hydroxy-1, 4-benzoxazine derivative | 华侨大学 | 2021-11-30 | — | — | CN | disclosed |