Succinimide

Succinimide

SCHEMBL28755992

C=C.C=CC.O=C1CCC(=O)N1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 5/20 0.61
NPC1 O15118 1/20 0.33
MAPK13 O15264 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33
KDM4E B2RXH2 1/20 0.32
LMNA P02545 1/20 0.32
CYP2C19 P33261 1/20 0.32
TOP2A P11388 1/20 0.32
TOP2B Q02880 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinimide SCHEMBL15823272 0.97 CRBN (0.65) CRBNNPC1MAPK13MAPK12MAPK11
Succinimide SCHEMBL28776541 0.97 CRBN (0.65) CRBNNPC1MAPK13MAPK12MAPK11
Succinimide SCHEMBL1001201 0.94 CRBN (0.61) CRBNNPC1MAPK13MAPK12MAPK11
Propene SCHEMBL28629425 0.86 CRBN (0.60) CRBNKDM4ELMNACYP2C19TOP2A
Propene SCHEMBL28176969 0.86 CRBN (0.68) CRBNKDM4ELMNACYP2C19TOP2A
Succinimide SCHEMBL7263756 0.85
Succinimide SCHEMBL28744286 0.85 CRBN (0.85) CRBNNPC1MAPK13MAPK12MAPK11
Succinimide SCHEMBL27977700 0.82 CRBN (0.69) CRBNNPC1MAPK13MAPK12MAPK11
Succinimide SCHEMBL3913660 0.82 CRBN (0.79) CRBNNPC1MAPK13MAPK12MAPK11
Succinimide SCHEMBL502041 0.79 CRBN (0.55) CRBNNPC1MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113825825-B Low corrosion organo-molybdenum compounds as lubricant additives 范德比尔特化学品有限责任公司 2022-08-02 CN disclosed
CN-114072485-B Less corrosive organic compounds as lubricant additives 范德比尔特化学品有限责任公司 2022-05-17 CN disclosed
CN-114072485-A Less corrosive organic compounds as lubricant additives 范德比尔特化学品有限责任公司 2022-02-18 CN disclosed
CN-113825825-A Low corrosion organomolybdenum compounds as lubricant additives 范德比尔特化学品有限责任公司 2021-12-21 CN disclosed