Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.33 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinimide SCHEMBL28776541 | 0.97 | CRBN (0.65) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL15823272 | 0.97 | CRBN (0.65) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL28755992 | 0.94 | CRBN (0.61) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Propene SCHEMBL28176969 | 0.86 | CRBN (0.68) | CRBNKDM4ELMNACYP2C19TOP2A | |
| Propene SCHEMBL28629425 | 0.86 | CRBN (0.60) | CRBNKDM4ELMNACYP2C19TOP2A | |
| Succinimide SCHEMBL27977700 | 0.82 | CRBN (0.69) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL3913660 | 0.82 | CRBN (0.79) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL1002212 | 0.82 | — | — | |
| Succinimide SCHEMBL502041 | 0.79 | CRBN (0.55) | CRBNNPC1MAPK13MAPK12MAPK11 | |
| Succinimide SCHEMBL9714970 | 0.79 | CRBN (0.55) | CRBNNPC1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575390-B2 | Branched succinimide dispersant compounds and methods of making the compounds | AFTON CHEMICAL CORPORATION (US) | 2013-11-05 | — | — | US | disclosed |
| US-20110118479-A1 | Branched Succinimide Dispersant Compounds and Methods of Making the Compounds | AFTON CHEMICAL CORPORATION (US) | 2011-05-19 | — | — | US | disclosed |
| US-7875747-B2 | directed to a dispersant compound comprising the reaction product of (i) a hydrocarbyl carbonyl compound, (ii) a polycarbonyl compound having at least three carbonyl acylating functions, and (iii) a primary amine moiety of a polyamine and methods of making dispersants | AFTON CHEMICAL CORPORATION (US) | 2011-01-25 | — | — | US | disclosed |
| CN-101235146-A | Compounds and lubricating compositions containing the compounds | AFTON CHEMICAL CORP (US) | 2008-08-06 | — | — | CN | disclosed |
| US-20080182767-A1 | Compounds and Lubricating Compositions Containing the Compounds | AFTON CHEMICAL CORPORATION | 2008-07-31 | — | — | US | disclosed |
| US-20080085845-A1 | BRANCHED SUCCINIMIDE DISPERSANT COMPOUNDS AND METHODS OF MAKING THE COMPOUNDS | AFTON CHEMICAL CORPORATION | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118479-A1 | Branched Succinimide Dispersant Compounds and Methods of Making the Compounds | SRM, DLST, ODC1 | CRBN 2578/4885NPC1 2157/4885MAPK13 3133/4885 |
| US-20080085845-A1 | BRANCHED SUCCINIMIDE DISPERSANT COMPOUNDS AND METHODS OF MAKING THE COMPOUNDS | SRM, DLST, ODC1 | CRBN 2578/4885NPC1 2157/4885MAPK13 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.