Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 14/20 | 0.67 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.57 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870134 | 0.88 | HTR2C (0.53) | HTR2CHAVCR2PIK3CAKDM4EMEN1 | |
| SCHEMBL13942978 | 0.80 | HTR2C (1.00) | HTR2CBCDIN3DKDM4EMEN1ALDH1A1 | |
| SCHEMBL2860019 | 0.80 | PIK3CA (0.58) | HTR2CHAVCR2PIK3CABCDIN3DKDM4E | |
| SCHEMBL13087256 | 0.79 | GAA (0.78) | HTR2CHAVCR2KDM4EMEN1ALDH1A1 | |
| SCHEMBL31194469 | 0.79 | PDE5A (0.61) | HTR2CPIK3CABCDIN3DKDM4EMEN1 | |
| SCHEMBL13944190 | 0.78 | HTR2C (1.00) | HTR2CBCDIN3DKDM4EMEN1ALDH1A1 | |
| SCHEMBL3751359 | 0.77 | HTR2C (1.00) | HTR2CBCDIN3DKDM4EMEN1ALDH1A1 | |
| SCHEMBL3174435 | 0.76 | PIK3CA (0.60) | HTR2CPIK3CABCDIN3DKDM4EMEN1 | |
| SCHEMBL13944354 | 0.76 | HTR2C (0.77) | HTR2CBCDIN3DKDM4EMEN1ALDH1A1 | |
| SCHEMBL2855842 | 0.75 | HTR2C (0.48) | HTR2CPIK3CABCDIN3DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |