Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCDIN3D | Q7Z5W3 | 4/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2864782 | 0.86 | MEN1 (0.53) | HTR2CABL1BCRNPC1RAB9A | |
| SCHEMBL2810178 | 0.81 | GAA (0.56) | HTR2CABL1BCRNPC1RAB9A | |
| SCHEMBL2804510 | 0.80 | NPC1 (0.47) | HTR2CABL1BCRNPC1RAB9A | |
| SCHEMBL2875609 | 0.75 | HTR2C (0.67) | HTR2CBCDIN3DPIK3CAMAPT | |
| SCHEMBL2832666 | 0.74 | SRC (0.59) | HTR2CABL1MAPT | |
| SCHEMBL2808009 | 0.71 | HTR2C (0.60) | HTR2C | |
| SCHEMBL3185882 | 0.71 | KDM4C (0.47) | GGPS1 | |
| SCHEMBL2856614 | 0.71 | PDE5A (0.55) | PIK3CAMAPTGGPS1 | |
| SCHEMBL2785338 | 0.71 | SRC (0.56) | ABL1BCRNPC1RAB9A | |
| SCHEMBL30782425 | 0.70 | XDH (0.60) | ABL1BCRNPC1RAB9AXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |