Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 7/20 | 0.58 |
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.49 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.48 |
| ▸ | BCDIN3D | Q7Z5W3 | 3/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2870134 | 0.87 | HTR2C (0.53) | PIK3CAHTR2CHAVCR2MAPTMEN1 | |
| SCHEMBL2875609 | 0.80 | HTR2C (0.67) | PIK3CAHTR2CHAVCR2BCDIN3DMAPT | |
| SCHEMBL31194469 | 0.74 | PDE5A (0.61) | PIK3CAHTR2CBCDIN3DMAPTMEN1 | |
| SCHEMBL3184819 | 0.74 | PIK3CA (0.54) | PIK3CAHTR2CGGPS1BCDIN3DBTK | |
| SCHEMBL2806838 | 0.73 | PIK3CA (0.61) | PIK3CAGGPS1BCDIN3DBTKMAPT | |
| SCHEMBL2804510 | 0.73 | NPC1 (0.47) | PIK3CAHTR2CHAVCR2GGPS1MAPT | |
| SCHEMBL3174574 | 0.73 | PIK3CA (0.64) | PIK3CAHTR2CGGPS1BCDIN3DBTK | |
| SCHEMBL13087256 | 0.72 | GAA (0.78) | HTR2CHAVCR2MAPTMEN1KMT2A | |
| SCHEMBL3175599 | 0.71 | PIK3CA (0.62) | PIK3CAHTR2CBCDIN3DBTKMAPT | |
| SCHEMBL3181720 | 0.70 | PIK3CA (0.63) | PIK3CAHTR2CGGPS1BCDIN3DBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |