Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28756081 | 0.86 | SRC (0.40) | MEN1KMT2ASRCSYKGSK3A | |
| SCHEMBL16829076 | 0.83 | SRC (0.37) | MEN1KMT2ATP53GAAALDH1A1 | |
| SCHEMBL16829092 | 0.78 | MAPK14 (0.43) | MEN1KMT2ATP53GAAALDH1A1 | |
| SCHEMBL28756073 | 0.78 | MAPK14 (0.41) | MEN1KMT2AALDH1A1SRCSYK | |
| SCHEMBL28756194 | 0.78 | GSK3A (0.39) | SRCSYKGSK3AMAPK14 | |
| SCHEMBL16829431 | 0.77 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1SRCSYK | |
| SCHEMBL28756114 | 0.75 | GSK3A (0.39) | MEN1KMT2ATP53SRCSYK | |
| SCHEMBL19434654 | 0.69 | ALDH1A1 (0.36) | MEN1KMT2ATP53ALDH1A1MAPK14 | |
| SCHEMBL28664475 | 0.69 | MAPT (0.38) | MEN1KMT2ATP53ALDH1A1SRC | |
| SCHEMBL29728524 | 0.69 | RXRA (0.35) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113717162-A | Urea derivatives as kinase inhibitors | 奥苏拉收购有限公司 | 2021-11-30 | — | — | CN | disclosed |