Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942250 | 0.84 | MAPT (0.47) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL28756255 | 0.82 | MAPT (0.46) | ALDH1A1MAPTLMNAGLATHRB | |
| SCHEMBL28756235 | 0.71 | MDM2 (0.47) | ALDH1A1MAPTLMNAGAAMEN1 | |
| SCHEMBL28756236 | 0.71 | MDM2 (0.47) | ALDH1A1MAPTLMNAGAAMEN1 | |
| SCHEMBL28756297 | 0.66 | MAPT (0.43) | ALDH1A1MAPTLMNAGAAMEN1 | |
| SCHEMBL13019793 | 0.65 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAKMT2AATM | |
| SCHEMBL28756250 | 0.65 | ALDH1A1 (0.36) | ALDH1A1MAPTGAAMEN1KMT2A | |
| SCHEMBL10720069 | 0.64 | ALDH1A1 (0.40) | ALDH1A1MAPTGLATHRBMEN1 | |
| SCHEMBL9507469 | 0.64 | CYSLTR2 (0.48) | ALDH1A1MAPTLMNAGAANOS3 | |
| SCHEMBL9507472 | 0.64 | CYSLTR2 (0.48) | ALDH1A1MAPTLMNAGAANOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507177-B | Method for preparing functionalized 2- (3-oxo-isoindoline-1-subunit) methyl acetate from carbon dioxide | 常州大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-114507177-A | Method for preparing functionalized 2- (3-oxoisoindoline-1-subunit) methyl acetate from carbon dioxide | 常州大学 | 2022-05-17 | — | — | CN | disclosed |