Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ACP3 | P15309 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30774302 | 0.84 | TDP1 (0.74) | TDP1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL7565966 | 0.84 | TDP1 (0.74) | TDP1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL31204231 | 0.79 | TDP1 (0.67) | TDP1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL4070603 | 0.77 | TDP1 (0.65) | TDP1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL29875700 | 0.77 | TDP1 (0.65) | TDP1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL18489066 | 0.77 | TDP1 (0.65) | TDP1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL9678690 | 0.77 | TDP1 (0.69) | TDP1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL9678693 | 0.77 | TDP1 (0.69) | TDP1MEN1KMT2AATML3MBTL1 | |
| SCHEMBL2266756 | 0.76 | MCL1 (0.62) | MEN1KMT2AATML3MBTL1KDM4E | |
| SCHEMBL11525938 | 0.76 | EPHX1 (0.48) | TDP1MEN1KMT2AATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010083501-A2 | ALPHA-HELIX MIMETIC USING A 2,5-OLIGOPYRIMIDINE SCAFFOLD | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010083501-A2 | ALPHA-HELIX MIMETIC USING A 2,5-OLIGOPYRIMIDINE SCAFFOLD | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-07-22 | — | — | WO | disclosed |