Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | VNN1 | O95497 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29875700 | 1.00 | TDP1 (0.65) | TDP1ATML3MBTL1KMT2AMEN1 | |
| SCHEMBL28879925 | 0.90 | TDP1 (0.53) | TDP1ATML3MBTL1KMT2AMEN1 | |
| SCHEMBL7565966 | 0.88 | TDP1 (0.74) | TDP1ATML3MBTL1KMT2AMEN1 | |
| SCHEMBL30774302 | 0.88 | TDP1 (0.74) | TDP1ATML3MBTL1KMT2AMEN1 | |
| SCHEMBL7196924 | 0.87 | TDP1 (0.62) | TDP1ATML3MBTL1KMT2AMEN1 | |
| SCHEMBL29875565 | 0.87 | TDP1 (0.62) | TDP1ATML3MBTL1KMT2AMEN1 | |
| SCHEMBL28879878 | 0.84 | TDP1 (0.46) | TDP1ATML3MBTL1KMT2AMEN1 | |
| Propionic Acid SCHEMBL28091563 | 0.84 | TDP1 (0.86) | TDP1ATML3MBTL1KMT2AMEN1 | |
| SCHEMBL31204231 | 0.83 | TDP1 (0.67) | TDP1ATML3MBTL1KMT2AMEN1 | |
| SCHEMBL8400463 | 0.82 | IAPP (0.58) | TDP1ACP3KDM4ECYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240024497-A1 | METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES | CIDARA THERAPEUTICS, INC. | 2024-01-25 | — | — | US | disclosed |
| US-11833213-B2 | Compositions and methods for the treatment of viral infections | CIDARA THERAPEUTICS, INC. (US) | 2023-12-05 | — | — | US | disclosed |
| EP-4139275-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | Syneurx International (Taiwan) Corp. (TW) | 2023-03-01 | — | — | EP | disclosed |
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| WO-2021213500-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-10-28 | — | — | WO | disclosed |
| US-20210228727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2021-07-29 | — | — | US | disclosed |
| US-20180169641-A1 | BENZO[H]QUINOLINE LIGANDS AND COMPLEXES THEREOF | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 2018-06-21 | — | — | US | disclosed |
| US-20180148465-A1 | PROCESS | UNIVERSITA DEGLI STUDI DI UDINE (IT) | 2018-05-31 | — | — | US | disclosed |
| US-9243238-B2 | Synthetic enzymes derived from computational design | UNIVERSITY OF WASHINGTON (US) | 2016-01-26 | — | — | US | disclosed |
| EP-1819684-B1 | SUBSTITUTED PIPERAZINES AS CB1 ANTAGONISTS | INTERVET INT BV (NL) | 2013-08-07 | — | — | EP | disclosed |
| EP-1392280-A2 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | Abbott GmbH & Co. KG (DE) | 2004-03-03 | — | — | EP | disclosed |
| US-20030212123-A1 | COX-2 selective carprofen for treating pain and inflammation in dogs | PFIZER INC. | 2003-11-13 | — | — | US | disclosed |
| US-20030096826-A1 | Arylsulfonamide ethers, and methods of use thereof | WARNER-LAMBERT COMPANY | 2003-05-22 | — | — | US | disclosed |
| WO-2002089749-A2 | ARYLSULFONAMIDE ETHERS, AND METHODS OF USE THEREOF | ABBOTT GMBH & CO.KG (DE) | 2002-11-14 | — | — | WO | disclosed |
| EP-0822174-B1 | Process for the preparation of a naphthylbutanone | ARCHIMICA SPA (IT) | 2000-05-31 | — | — | EP | disclosed |
| EP-0988034-A1 | COX-2 SELECTIVE CARPROFEN FOR TREATING PAIN AND INFLAMMATION IN DOGS | PFIZER INC. (US) | 2000-03-29 | — | — | EP | disclosed |
| WO-1998050033-A1 | COX-2 SELECTIVE CARPROFEN FOR TREATING PAIN AND INFLAMMATION IN DOGS | PFIZER INC. (US) | 1998-11-12 | — | — | WO | disclosed |
| US-5777170-A | Process for the preparation of a naphthylbutanone | ARCHIMICA SPA (IT) | 1998-07-07 | — | — | US | disclosed |
| EP-0822174-A1 | Process for the preparation of a naphthylbutanone | Archimica S.p.A. (IT) | 1998-02-04 | — | — | EP | disclosed |
| US-3966814-A | PERIPHERAL VASODILATORS, ANTIHISTAMINES, SPASMOLYTICS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180169641-A1 | BENZO[H]QUINOLINE LIGANDS AND COMPLEXES THEREOF | BRD4, NQO1, NQO2 | TDP1 1608/4885ATM 3277/4885L3MBTL1 3418/4885 |
| US-20240024497-A1 | METHODS FOR THE SYNTHESIS OF PROTEIN-DRUG CONJUGATES | RNGTT, RNMT, DNPEP | TDP1 3431/4885ATM 4789/4885L3MBTL1 3063/4885 |
| US-20030096826-A1 | Arylsulfonamide ethers, and methods of use thereof | CASP1, IRAK1, STS | TDP1 1116/4885ATM 2414/4885L3MBTL1 2397/4885 |
| US-20030212123-A1 | COX-2 selective carprofen for treating pain and inflammation in dogs | PTGES2, PTGER2, PTGS2 | TDP1 3929/4885ATM 4006/4885L3MBTL1 2096/4885 |
| US-20210228727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTIONS | FCGR3B, ALB, FCGR1A | TDP1 4479/4885ATM 4701/4885L3MBTL1 3340/4885 |
| US-11833213-B2 | Compositions and methods for the treatment of viral infections | FCGR3B, ALB, FCGR1A | TDP1 4479/4885ATM 4701/4885L3MBTL1 3340/4885 |
| US-20180148465-A1 | PROCESS | OSTC, AP2S1, LGALS4 | TDP1 3676/4885ATM 2387/4885L3MBTL1 4827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.