Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629456 | 0.85 | ALDH1A1 (0.46) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL27610264 | 0.85 | ALDH1A1 (0.46) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL28523274 | 0.84 | ALDH1A1 (0.42) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL28523272 | 0.84 | ALDH1A1 (0.42) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL5539609 | 0.84 | CHRM1 (0.47) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL28531344 | 0.84 | CHRM1 (0.47) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL2224586 | 0.81 | ALDH1A1 (0.47) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL17984901 | 0.79 | ALDH1A1 (0.44) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL5316860 | 0.79 | ALDH1A1 (0.41) | ALDH1A1PKMKMT2ASOS1MITF | |
| SCHEMBL12517676 | 0.78 | ALDH1A1 (0.38) | ALDH1A1PKMKMT2ASOS1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |