SCHEMBL28523274

SCHEMBL28523274

O=[N+]([O-])c1cn(CC(O)CO)c(Cl)n1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
PKM P14618 2/20 0.41
KMT2A Q03164 3/20 0.40
SOS1 Q07889 1/20 0.38
MITF O75030 1/20 0.37
CHRM1 P11229 1/20 0.35
POLB P06746 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 1/20 0.35
AHCY P23526 1/20 0.34
ADORA2A P29274 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28523272 1.00 ALDH1A1 (0.42) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL28531344 0.88 CHRM1 (0.47) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL5539609 0.88 CHRM1 (0.47) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL15442198 0.86 ALDH1A1 (0.40) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL13280994 0.86 ALDH1A1 (0.40) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL13281114 0.86 ALDH1A1 (0.40) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL17984901 0.84 ALDH1A1 (0.44) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL28756702 0.84 ALDH1A1 (0.43) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL27629456 0.84 ALDH1A1 (0.46) ALDH1A1PKMKMT2ASOS1MITF
SCHEMBL27610264 0.84 ALDH1A1 (0.46) ALDH1A1PKMKMT2ASOS1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110483549-B Preparation method of nitroimidazole pyran antituberculosis drug 沈阳药科大学 2021-03-05 CN claimed
CN-110483549-B Preparation method of nitroimidazole pyran antituberculosis drug 沈阳药科大学 2021-03-05 CN disclosed