Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 10/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 4/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360812 | 0.82 | IRAK4 (0.44) | IRAK4AAK1PIK3C3TGFBR1 | |
| SCHEMBL5354912 | 0.82 | MAPK14 (0.47) | IRAK4CYP3A4PIK3C3TGFBR1 | |
| SCHEMBL5353074 | 0.82 | RIPK3 (0.45) | GSK3BRIPK3 | |
| SCHEMBL5352411 | 0.80 | GSK3B (0.45) | IRAK4AAK1CYP3A4PIK3C3TGFBR1 | |
| SCHEMBL5349844 | 0.80 | TGFBR1 (0.40) | IRAK4AAK1PIK3C3TGFBR1GSK3B | |
| SCHEMBL5355784 | 0.80 | IRAK4 (0.42) | IRAK4AAK1CYP3A4PIK3C3TGFBR1 | |
| SCHEMBL5349670 | 0.79 | CDK9 (0.42) | IRAK4AAK1PIK3C3TGFBR1GSK3B | |
| SCHEMBL10129965 | 0.78 | PIK3C3 (0.43) | IRAK4AAK1CYP3A4PIK3C3TGFBR1 | |
| SCHEMBL1104982 | 0.75 | RIPK3 (0.44) | IRAK4AAK1PIK3C3TGFBR1GSK3B | |
| SCHEMBL5251219 | 0.74 | EGFR (0.57) | IRAK4AAK1PIK3C3TGFBR1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100519552-C | Pyrazole compounds | UBE INDUSTRIES (JP) | 2009-07-29 | — | — | CN | disclosed |
| CN-1684953-A | Pyrazole compounds | UBE INDUSTRIES (JP) | 2005-10-19 | — | — | CN | disclosed |