Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27760958 | 0.88 | BCL9 (0.51) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL3017398 | 0.85 | BCL9 (0.51) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL27399887 | 0.85 | BCL9 (0.55) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL28001907 | 0.85 | KDM4E (0.37) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL4799237 | 0.83 | BCL9 (0.49) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL28810763 | 0.83 | ALDH1A1 (0.50) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL11229499 | 0.82 | BCL9 (0.44) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL27779212 | 0.81 | BCL9 (0.48) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL1667992 | 0.81 | CA2 (0.48) | BCL9CTNNB1KMT2AALDH1A1KDM4E | |
| SCHEMBL7773613 | 0.80 | CA2 (0.47) | BCL9CTNNB1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882554-A | Carboxylic acid compounds and pharmaceutical compositions containing them as active ingredient | ONO PHARMACEUTICAL CO (JP) | 2006-12-20 | — | — | CN | disclosed |