Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722835 | 1.00 | USP30 (0.41) | USP30GPR119HDAC1HDAC2BACE1 | |
| SCHEMBL29511830 | 0.86 | RORC (0.43) | USP30GPR119HDAC1HDAC2RORC | |
| SCHEMBL22462815 | 0.86 | RORC (0.43) | USP30GPR119HDAC1HDAC2RORC | |
| SCHEMBL22462808 | 0.83 | NFE2L2 (0.39) | — | |
| SCHEMBL21723087 | 0.76 | RORC (0.42) | USP30GPR119HDAC1HDAC2RORC | |
| SCHEMBL20971857 | 0.76 | GRM5 (0.45) | GPR119KMT2AF13A1TGM2TGM1 | |
| SCHEMBL30836066 | 0.76 | CYP1A1 (0.43) | GPR119RORCPDE4B | |
| SCHEMBL21722865 | 0.76 | RORC (0.41) | USP30GPR119HDAC1HDAC2RORC | |
| SCHEMBL21381806 | 0.75 | MAPT (0.47) | USP30GPR119HDAC1HDAC2RORC | |
| SCHEMBL20015276 | 0.75 | DPP4 (0.53) | GPR119KMT2ADPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114650994-A | Radiolabelled compounds | 豪夫迈·罗氏有限公司 | 2022-06-21 | — | — | CN | disclosed |