Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339164 | 0.82 | CNR1 (0.52) | CNR1 | |
| SCHEMBL6776605 | 0.79 | KDM4E (0.40) | CNR1PDE4BKMT2AKDM4EMAPT | |
| SCHEMBL6768891 | 0.70 | CNR1 (0.39) | CNR1PDE4BKMT2AKDM4EALDH1A1 | |
| SCHEMBL27889663 | 0.69 | MAPK1 (0.48) | RIPK1SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL14806692 | 0.67 | CNR1 (0.53) | CNR1 | |
| SCHEMBL9183491 | 0.67 | MAPK1 (0.68) | POLBRIPK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL27653228 | 0.67 | CNR1 (0.50) | CNR1 | |
| SCHEMBL6766433 | 0.67 | CNR1 (0.44) | CNR1HPGD | |
| SCHEMBL6515355 | 0.65 | ALDH1A1 (0.46) | POLBADORA2APDE4BRIPK1HSD11B1 | |
| SCHEMBL4172241 | 0.65 | ALDH1A1 (0.52) | HDAC1PDE4BRIPK1HSD11B1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777605-A | Cannabined receptor ligands and uses thereof | PFIZER (US) | 2006-05-24 | — | — | CN | disclosed |