Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2679077 | 0.86 | NPSR1 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6123646 | 0.84 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL5768692 | 0.83 | LMNA (0.50) | ALDH1A1LMNA | |
| SCHEMBL5368660 | 0.81 | PDE4B (0.57) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL15333179 | 0.80 | SMN1; SMN2 (0.43) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL15330966 | 0.78 | CNR1 (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL15329768 | 0.78 | SMN1; SMN2 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL31327096 | 0.78 | SMN1; SMN2 (0.55) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2560106 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL2559493 | 0.74 | RXRA (0.40) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005061504-A1 | BICYCLIC PYRIDAZINONE CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |