Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | CCNK | O75909 | 1/20 | 0.48 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | TEK | Q02763 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850347 | 0.86 | CYP19A1 (0.58) | NPC1RAB9AHSP90AB1CYP19A1KDR | |
| SCHEMBL19813136 | 0.85 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL12219083 | 0.83 | MEN1 (0.64) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL20393727 | 0.81 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL29094364 | 0.81 | MEN1 (0.58) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL3477949 | 0.79 | KDR (0.46) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL3432522 | 0.79 | CACNA1G (0.50) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL23431940 | 0.79 | HSP90AA1 (0.63) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL2820279 | 0.79 | NOTUM (0.69) | MEN1KMT2ANPC1RAB9AHSP90AA1 | |
| SCHEMBL19611853 | 0.79 | MEN1 (0.56) | MEN1KMT2ANPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1910151-A | Cyclic amine derivative with heteroaryl ring | SANKYO CO (JP) | 2007-02-07 | — | — | CN | disclosed |