Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | PPARD | Q03181 | 6/20 | 0.53 |
| ▸ | PPARA | Q07869 | 6/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 3/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2873060 | 0.97 | ALDH1A1 (0.55) | ALDH1A1PPARGPPARDPPARACYP19A1 | |
| SCHEMBL31076236 | 0.89 | ALDH1A1 (0.46) | ALDH1A1PPARGPPARDPPARACYP19A1 | |
| SCHEMBL2011462 | 0.82 | ALDH1A1 (0.52) | ALDH1A1PPARGPPARDPPARALMNA | |
| SCHEMBL2010277 | 0.82 | ALDH1A1 (0.52) | ALDH1A1PPARGPPARDPPARALMNA | |
| SCHEMBL2011728 | 0.82 | ALDH1A1 (0.52) | ALDH1A1PPARGPPARDPPARALMNA | |
| SCHEMBL2011072 | 0.82 | ALDH1A1 (0.52) | ALDH1A1PPARGPPARDPPARALMNA | |
| SCHEMBL17645156 | 0.82 | MEN1 (0.61) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| SCHEMBL17645154 | 0.82 | MEN1 (0.61) | ALDH1A1MAPTHPGDKMT2AMEN1 | |
| Methane SCHEMBL2009500 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PPARGPPARDPPARALMNA | |
| Methane SCHEMBL2012154 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PPARGPPARDPPARALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9867795-B2 | Nitrated lipids and methods of making and using thereof | THE UAB RESEARCH FOUNDATION (US) | 2018-01-16 | — | — | US | disclosed |
| US-20170119717-A1 | NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2017-05-04 | — | — | US | disclosed |
| US-9522156-B2 | Nitrated lipids and methods of making and using thereof | THE UAB RESEARCH FOUNDATION (US) | 2016-12-20 | — | — | US | disclosed |
| US-20160151391-A1 | NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF | THE UAB RESEARCH FOUNDATION | 2016-06-02 | — | — | US | disclosed |
| US-9295678-B2 | Nitrated lipids and methods of making and using thereof | THE UAB RESEARCH FOUNDATION (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150246059-A1 | NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF | THE UAB RESEARCH FOUNDATION | 2015-09-03 | — | — | US | disclosed |
| US-9006473-B2 | Nitrated lipids and methods of making and using thereof | THE UAB RESEARCH FOUNDATION (US) | 2015-04-14 | — | — | US | disclosed |
| US-20130210917-A1 | Nitrated Lipids and Methods of Making and Using Thereof | THE UAB RESEARCH FOUNDATION (US) | 2013-08-15 | — | — | US | disclosed |
| US-8309526-B2 | Nitrated lipids and methods of making and using thereof | THE UAB RESEARCH FOUNDATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-20100331268-A1 | Nitrated Lipids and Methods of Making and Using Thereof | THE UAB RESEARCH FOUNDATION (US) | 2010-12-30 | — | — | US | disclosed |
| US-7776916-B2 | Nitrated lipids and methods of making and using thereof | THE UAB RESEARCH FOUNDATION (US) | 2010-08-17 | — | — | US | disclosed |
| US-20070232579-A1 | Nitrated Lipids and Methods of Making and Using Thereof | UAB RESEARCH FOUNDATION, THE (US) | 2007-10-04 | — | — | US | disclosed |
| WO-2005110396-A2 | NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF | UAB RESEARCH FOUNDATION (US) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210917-A1 | Nitrated Lipids and Methods of Making and Using Thereof | FASN, NOS2, LIPA | ALDH1A1 884/4885PPARG 923/4885PPARD 775/4885 |
| US-20150246059-A1 | NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF | FASN, NOS2, LIPA | ALDH1A1 884/4885PPARG 923/4885PPARD 775/4885 |
| US-20070232579-A1 | Nitrated Lipids and Methods of Making and Using Thereof | FASN, NOS2, LIPA | ALDH1A1 884/4885PPARG 923/4885PPARD 775/4885 |
| US-20170119717-A1 | NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF | FASN, NOS2, LIPA | ALDH1A1 884/4885PPARG 923/4885PPARD 775/4885 |
| US-20160151391-A1 | NITRATED LIPIDS AND METHODS OF MAKING AND USING THEREOF | FASN, NOS2, LIPA | ALDH1A1 884/4885PPARG 923/4885PPARD 775/4885 |
| US-20100331268-A1 | Nitrated Lipids and Methods of Making and Using Thereof | FASN, NOS2, LIPA | ALDH1A1 884/4885PPARG 923/4885PPARD 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.