Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SI | P14410 | 2/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29040702 | 0.87 | MGAM (0.40) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL2701579 | 0.79 | GAA (0.60) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL29101713 | 0.78 | — | — | |
| SCHEMBL29004726 | 0.78 | — | — | |
| Water SCHEMBL2703341 | 0.77 | GAA (0.57) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL29066780 | 0.75 | DGKA (0.45) | ADRA2AADRA1A | |
| SCHEMBL29066752 | 0.75 | ADRA2A (0.30) | ADRA2AADRA1A | |
| SCHEMBL649327 | 0.75 | MGAM (0.55) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL16411225 | 0.75 | MGAM (0.55) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL23041373 | 0.73 | MGAM (0.52) | MGAMGAASIMGAM2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283920-B | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2024-04-16 | — | — | CN | disclosed |
| CN-117813302-A | Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-116670143-A | Modulators of cystic fibrosis transmembrane conductance regulator | 弗特克斯药品有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116490507-A | Heterocyclic condensation CDC7 kinase inhibitors for the treatment of cancer | 薛定谔公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-116283920-A | 2, 4-disubstituted pyridine compound and application thereof | 贵州医科大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-100582104-C | Oxadiazolone derivatives as PPAR delta agonists | SANOFI AVENTIS DEUTSCHLAND | 2010-01-20 | — | — | CN | disclosed |
| CN-1938300-A | Oxadiazolone derivatives as PPAR delta agonists | SANOFI AVENTIS DEUTSCHLAND (DE) | 2007-03-28 | — | — | CN | disclosed |